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Erythrodiol
Basic Information
- CAS No.: 545-48-2
Physical properties
Product Description
Top Quality Chinese Manufacturer supply 545-48-2 Erythrodiol
- Molecular Formula: C30H50O2
- Molecular Weight: 442.726
- Melting Point: 230-231 °C(lit.)
- Boiling Point: 520.5 °C at 760 mmHg
- PKA: 15.09±0.10(Predicted)
- Flash Point: 209.9 °C
- PSA： 40.46000
- Density: 1.05 g/cm3
- LogP: 7.14130
545-48-2 Relevant articles
Biocatalytic allylic hydroxylation of unsaturated triterpenes and steroids by Bacillus megaterium CGMCC 1.1741
Ge, Haixia,Li, Guolong,Shen, Pingping,Wang, Wei,Wang, Weiwei,Xu, Shaohua,Yu, Boyang,Zhang, Jian
, (2020/04/20)
In this study, we described the microbia...
An improved scalable synthesis of α- and β-amyrin
Serbian, Immo,Csuk, René
, (2018/07/13)
The synthesis of α- and β-amyrin was acc...
Synthesis of oleanolic acid analogues and their cytotoxic effects on 3T3 cell line
Tuncay, Salih,Senol, Halil,Guler, Eray Metin,Ocal, Nuket,Secen, Hasan,Kocyigit, Abdurrahim,Topcu, Gulacti
, p. 617 - 625 (2018/08/17)
Background: Oleanolic acid (OA) is a kno...
Semi-synthesis and Structure–Activity Relationship of Neuritogenic Oleanene Derivatives
Bian, Linglin,Cao, Shining,Cheng, Lihong,Nakazaki, Atsuo,Nishikawa, Toshio,Qi, Jianhua
supporting information, p. 1972 - 1977 (2018/09/06)
(3S,4R)-23,28-Dihydroxyolean-12-en-3-yl ...
545-48-2 Process route
-
-
C50 H82 O14
-
-
1139-97-5,1139-98-6,1851-12-3,3353-52-4,6163-35-5,14184-49-7,19146-17-9,22248-57-3,34361-56-3,34361-57-4,57793-53-0,7506-68-5
2,3,4,6-tetra-O-methyl-D-glucopyranose
-
-
508-02-1
Oleanolic acid
-
-
545-48-2,55869-95-9,118204-21-0
erythrodiol
| Conditions | Yield |
|---|---|
|
With
lithium aluminium tetrahydride; sulfuric acid;
Multistep reaction;
|
-
-
508-02-1
Oleanolic acid
-
-
545-48-2,55869-95-9,118204-21-0
erythrodiol
| Conditions | Yield |
|---|---|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 ℃;
Reflux;
|
96%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 3.5h;
Heating;
|
95%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at -12 - 20 ℃;
for 24h;
Inert atmosphere;
|
94%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 1h;
Reflux;
|
92%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 5h;
Reflux;
Sealed tube;
Inert atmosphere;
|
90.9%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 1.5h;
Reflux;
|
85%
|
|
Oleanolic acid;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 3h;
Reflux;
With
water;
In
tetrahydrofuran;
|
82%
|
|
With
lithium aluminium tetrahydride;
In
diethyl ether;
for 48h;
|
75%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 20 ℃;
for 4h;
|
69%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 ℃;
for 9.5h;
Reagent/catalyst;
Time;
Temperature;
Inert atmosphere;
Reflux;
|
60%
|
|
With
tetrahydrofuran; lithium aluminium tetrahydride; diethyl ether;
|
|
|
Multi-step reaction
with
2
steps
1: methanol. KOH-solution
2: dioxane; copper oxide-chromium oxide / 260 °C / 220652 Torr / Hydrogenation
With
1,4-dioxane; potassium hydroxide; copper oxide-chromium oxide;
|
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 3h;
Heating;
|
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 ℃;
for 3h;
Reflux;
|
|
|
Multi-step reaction
with
2
steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h
1.2: 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C
With
lithium aluminium tetrahydride; potassium carbonate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
|
|
|
Multi-step reaction
with
2
steps
1: potassium carbonate / N,N-dimethyl-formamide / 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran
With
lithium aluminium tetrahydride; potassium carbonate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
|
|
|
With
lithium aluminium tetrahydride;
|
545-48-2 Upstream products
-
17884-88-7
myricadiol
-
508-02-1
Oleanolic acid
-
1724-17-0
oleanolic acid methyl ester
-
141-52-6
sodium ethanolate
545-48-2 Downstream products
-
33608-08-1
3-oxoolean-12-en-28-al
-
1896-77-1
erythrodiol diacetate
-
19897-41-7
3β-hydroxy-11α,12α-epoxy-olean-28,13β-olide
-
7089-38-5
3β-acetoxy-28-hydroxy-ole-12-ene