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Thiazole-5-carboxylic acid
Basic Information
- CAS No.: 14527-41-4
Physical properties
Product Description
Thiazole-5-carboxylic acid 14527-41-4 with purity >99% Low price in stock
- Molecular Formula: C4H3NO2S
- Molecular Weight: 129.139
- Vapor Pressure: 0.000143mmHg at 25°C
- Melting Point: 190-198 °C
- Boiling Point: 319.236 °C at 760 mmHg
- PKA: 3.07±0.10(Predicted)
- Flash Point: 146.869 °C
- PSA： 78.43000
- Density: 1.525 g/cm3
- LogP: 0.84130
Thiazole-5-carboxylic acid(Cas 14527-41-4) Usage
InChI:InChI=1/C4H3NO2S/c6-4(7)3-1-5-2-8-3/h1-2H,(H,6,7)/p-1
14527-41-4 Relevant articles
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Mislow
, p. 729,736, 737 (1948)
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Erne
, p. 138,141 (1953)
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ISOINDOLINONE COMPOUNDS
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Page/Page column 184-185, (2021/04/17)
Disclosed herein is a compound or pharma...
CARBOXYLATION CATALYSTS
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Paragraph 0093, (2013/04/13)
The use of a complex of the form Z—M—OR ...
Synthesis and antibacterial activities of pleuromutilin derivatives with thiazole-5-carboxamide and thioether moiety
Wang, Liang,Dai, Fu-Ying,Zhu, Jie,Dong, Kui-Kui,Wang, Yu-Liang,Chen, Tian
experimental part, p. 313 - 316 (2011/10/05)
Seven novel pleuromutilin derivatives wi...
Carboxylation of C-H bonds using N -heterocyclic carbene gold(I) complexes
Boogaerts, Ine I. F.,Nolan, Steven P.
supporting information; experimental part, p. 8858 - 8859 (2010/08/21)
A highly efficient [(NHC)AuI]-based (NHC...
14527-41-4 Process route
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288-47-1
1,3-thiazole
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-
124-38-9,18923-20-1
carbon dioxide
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-
14527-41-4
thiazole-5-carboxylic acid
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-
14190-59-1
1,3-thiazole-2-carboxylic acid
| Conditions | Yield |
|---|---|
|
carbon dioxide;
With
AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene); potassium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
for 0.25h;
under 1125.11 Torr;
1,3-thiazole;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
under 1125.11 Torr;
With
hydrogenchloride;
In
tetrahydrofuran; water;
regioselective reaction;
|
61%
27% |
-
-
14527-41-4
thiazole-5-carboxylic acid
-
-
14190-59-1
1,3-thiazole-2-carboxylic acid
| Conditions | Yield |
|---|---|
|
With
[Au(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(OH)]; potassium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
With
hydrogenchloride;
In
tetrahydrofuran; water;
|
61%
27% |
14527-41-4 Upstream products
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3034-55-7
5-bromo-1,3-thiazole
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32955-22-9
ethyl thiazole-5-carboxylate
-
79265-30-8
2-(trimethylsilyl)thiazole
-
288-47-1
1,3-thiazole
14527-41-4 Downstream products
-
14527-44-7
methyl thiazole-5-carboxylate
-
90842-21-0
N-phenylthiazole-5-carboxamide
-
93336-06-2
thiazole-5-carbothioic acid anilide
-
30216-61-6
thiazole-5-carboxylic acid phenyl ester